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UK SmPCs for licensed GLP-1 receptor agonists advise counselling patients on the symptoms of thyroid tumours

Tirzepatide achieved MASH resolution rates of 44% to 62% across doses in the SYNERGY-NASH trial (up to 73% on the efficacy estimand at 15 mg)

Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: A randomised, placebo-controlled and active comparator-controlled phase 2 trial

This decision has significant implications for 503B compounding pharmacies that had been producing tirzepatide during the declared shortage period

Certain conditions like hypothyroidism could make weight loss more challenging

doi: 10.1016/j.molmet.2019.09.010 [DOI] [PMC free article] [PubMed] [Google Scholar] 58
