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While semaglutide activates only the GLP-1 receptor, tirzepatide is a dual agonist that activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

The more you have, the higher your resting metabolism, and the better your long-term outcomes for falls, fractures, cognition, glucose control, and longevity

Although our mouse studies suggest that tirzepatide stimulates insulin secretion predominantly through the GLP-1R, the species difference in receptor pharmacology may limit extension of this interpretation to humans 25,26
Glucagon is a hormone that tells your liver to break down sugar and release it into your blood

Check Our Offers Table of Contents: Why is GLP-1 therapy popular for medical weight loss

This gut-produced hormone has been receiving a lot of attention in the health niche given its revolutionary roles in metabolism, appetite suppression, and blood sugar management