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For women, weight loss tends to be a little slower-going than it is for men

Effects on blood glucose The SURPASS clinical trial programme assessed the efficacy and safety of tirzepatide as a treatment to improve glycaemic control in people with type 2 diabetes

Some of the most common side effects seen for semaglutide and tirzepatide are nausea, vomiting, abdominal pain, and constipation and gastroparesis

Its usually painless and affects the lower half of what you see

Oral contraceptives may have altered effectiveness

Since 2005, when the FDA approved the first GLP-1 RA, exenatide, numerous GLP-1 products have become available (see GLP-1 RAs for type 2 diabetes mellitus and obesity )