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Am J Physiol Endocrinol Metab 324: E449E460

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2 Gut-brain mechanisms of communication The human gut harbors an incredibly diverse community of bacteria, fungi, parasites, viruses and protozoa that form the GM and contribute to the synthesis of bioactive compounds such as SCFAs, neurotransmitters, tryptophan metabolites, and select vitamins, all essential to host physiology ( Lactobacilli spp., and reduced Faecalibacterium prausnitzii has been found in patients with Crohn's disease ( The GBA is a widely studied model for understanding how microbiota shifts influence CNS health

Conversely, using primary rat thyroid cells in culture, mRNA expression, and a functional response were observed after stimulation with GLP-1 RAs