glp-1 receptor agonist for weight loss Frontiers Glucagon-like peptide-1 receptor: mechanisms and

A few highlights: Accelerated eGFR decline during the year preceding a heart failure event Slower decline afterward but still exacerbated A parallel between eGFR slope and NYHA class, suggesting the kidney may be signaling congestion early These findings call for a shift in practice: instead of relying on static eGFR thresholds, tracking its trajectory over time could help us identify at-risk patients sooner and intervene before hospitalization

And are they worth trying

doi: 10.1530/JOE-20-0608 26 ChenJMeiALiuXBraunsteinZWeiYWangBet al

This and other trials have shown improvements in patients lipid profiles with the most pronounced impact on reduction of triglycerides

Liraglutide has been in shortage in the US since July 2023, according to an FDA database

Current microneedle patches achieve 4-18% bioavailability compared to 89% for subcutaneous injection