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58 Anaesthesia Several studies, including a retrospective audit and a matched pair case-control study of 205 pairs of patients undergoing gastroscopy, have shown that patients taking GLP-1 receptor agonists have higher rates of retained solid gastric contents

This modulation of excitatory neurotransmission may contribute to the observed effects of GLP-1R agonists on reward-related behaviors [34]

A neural basis for melanocortin4 receptorregulated appetite

5 tips for staying hydrated on a GLP-1 Staying hydrated on a GLP-1 is important to prevent dehydration, and may even support healthy weight loss

This highlights the critical role of titration and adherence in achieving optimal weight loss outcomes

Peripheral GLP-1/GLP-1RAs may also interact with the CNS indirectly by GLP-1R expressed on vagal afferent fibers, signaling via nodose ganglia (57) to the nucleus tractus solitarii within the brainstem