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Patients were on a stable dose of insulin prior to enrolment with no changes in insulin dose permitted during the run-in period

The FDA prescribing information for tirzepatide (Mounjaro and Zepbound) does not list thrombotic events as a known adverse effect

Retatrutide does not directly build muscle or stimulate muscle protein synthesis

Journal of Medicinal Chemistry, 58 (3), 10201037

CrossRef Metabolic dysfunction-associated steatotic liver disease-associated fibrosis and cardiac dysfunction in patients with type 2 diabetes Simona Cernea, Danusia Onior, Andrada Larisa Roiban, Theodora Benedek, Nora Rat World Journal of Cardiology.2024

To put that into perspective: Many participants also experienced improvements in: Waist circumference Blood pressure Cholesterol levels Blood sugar control Overall metabolic health Importantly, individual results can vary significantly depending on factors such as diet, exercise habits, medication adherence, sleep quality, and underlying health conditions