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Glucagon-like peptide 1 (GLP-1) receptor agonists' use during pregnancy: Safety data from regulatory clinical trials

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Hinsichtlich der Proliferation ergibt sich ein heterogenes Bild: Whrend Exendin-4 in mehreren Studien die Zellproliferation dosis- und zeitabhngig steigerte, inhibierten native GLP-1-Formen sowie Liraglutid berwiegend das Zellwachstum und die DNA-Synthese, was eine substanzspezifische Modulation zellulrer Prozesse unterstreicht

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