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This matters most in groups already vulnerable to changes in bone density, including: Post-menopausal women Adults over 50 Individuals with low resistance training exposure Athletes experiencing chronically low energy availability GLP-1 therapy is not contraindicated for these groups

A., Hussein, L., & Paliy, O

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Tirzepatide was removed from the FDA shortage list, and the compounding exemptions that allowed routine production of tirzepatide copies have largely expired