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Researchers now understand that GLP-1 operates as a metabolic hormone while also serving as an anti-inflammatory agent that functions within synovial spaces

10.1016/j.jsbmb.2009.12.005 18 BuchwaldH.EstokR.FahrbachK.BanelD.JensenM

Berberine attenuates hepatic oxidative stress in rats with non-alcoholic fatty liver disease via the Nrf2/ARE signalling pathway

"It's prescribed by the doctor, the person takes their medicine, they lose weight, but then life happens," Cook said

Non-GLP-1 alternatives like metformin, topiramate, bupropion-naltrexone, and zonisamide may also be used, either alone or in combination, depending on your needs

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