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188,208 Although a modest reduction in lean mass was observed at 12 months, muscle function, assessed via handgrip strength, improved significantly, the prevalence of sarcopenic obesity declined, and resting energy expenditure relative to lean mass increasedindicating enhanced metabolic efficiency

Daniel Drucker [Biomarker April 2023] Can GLP-1/GIP therapies improve long term health outcomes

Additionally, for individuals with type 2 diabetes, semaglutide GLP-1 aids in glycemic control by promoting insulin secretion and inhibiting glucagon release, helping stabilize blood sugar levels

This systematic review of low-to-moderate evidence on the GLP-1 user risk of perioperative regurgitation and aspiration will examine the ongoing challenges in developing evidence-based clinical guidelines for patients using GLP-1 RAs, particularly with respect to perioperative management