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Jacobson TA, Maki KC, Orringer CE, Jones PH, Kris-Etherton P, Sikand G, et al

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12,19-24 Weight loss was due to reductions in fat mass rather than lean tissue mass

Monitor your caloric intake: While weight loss is often the goal, losing weight too rapidly or eating fewer than 1,200 calories (for women) or 1,500 calories (for men) can send your body into a state of exhaustion

Dawes, P., L

While these effects often diminish as patients adjust to treatment, healthcare providers increasingly emphasize gradual dose escalation and comprehensive monitoring, ultimately enabling better patient outcomes and treatment adherence across diverse populations
