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Clinicians should also monitor nutritional risks associated with rapid weight loss, such as deficiencies in iron, folic acid, and B vitamins, to ensure the patient is pregnancy-ready rather than just weight-ready. Given that GLP-1RAs improving IVF outcomes remains limited, their appropriate positioning remains a metabolic optimization tool before ART rather than a standardized pretreatment regimen ( 7 From evidence to decision: estimating net benefit under uncertainty Clinical decisions around GLP-1RAs in fertility-focused PCOS care are rarely binary

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But GLP-1 medications are not part of the usual trend cycle