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This finding was confirmed and extended by a comprehensive metabolic phenotyping study, which showed that ablation of NTS PPG neurons did not affect meal patterns or energy expenditure in ad libitum feeding mice (Brierley et al., 2021)

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Transcriptomic analysis was conducted on liver tissues from Gipr fl/fl , Gipr Syn / , Glp1r fl/fl and Glp1r Wnt1 / mice treated with either vehicle or mGIPR-Ab/P1