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While constipation risk varies individually, understanding your genetic profile helps your provider anticipate side effects and adjust your starting dose or formulation strategy accordingly

Chem Biol Drug Design (2015) 86:148290

Risk Factors History of stomach issues or motion sickness Rapid dose increases Starting at higher doses Large, high-fat meals Eating too quickly Dehydration Existing metabolic disorders or obesity Female gender (noted in some studies) Metabolic disorders such as obesity exacerbate nausea

You administer the injection subcutaneously , typically once per week

[DOI] [PMC free article] [PubMed] [Google Scholar] [116].Fain JN (2006)

However, if intolerable side effects such as nausea or vomiting occur, the treatment is discontinued