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doi: 10.1210/en.2012-1272

Semaglutide Peptide (NN9935) is a synthetic GLP-1 analogue with two amino acid substitutions [Aib(8), Arg(34)] and a Lys26 fatty acid chain that prolong its half-life (7 days) and improve stability

A quick note on legal status: as of 2026, FDA-registered 503B outsourcing facilities can legally compound semaglutide when it meets specific quality and safety standards