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Description
Tirzepatide may also cause additional stomach issues such as constipation, belching, indigestion, and fatigue, and there is a possible risk of low blood sugar, especially when combined with other diabetes medications

However, GLP-1 receptors are also present in skeletal muscle tissue, where the medication can influence cellular ion balance and electrolyte handling

Tirzepatide, a dual GIPR/GLP-1R agonist approved for T2D and obesity, has shown preclinical neurobiological effects consistent with neuroprotection in models of diabetic neurodegeneration, Alzheimer-type amyloidosis, and Parkinsons disease

Changes in mood, energy, or cognitive function that coincide with starting therapy

Steroid hormones and excitability in the mammalian brain

(7) Use In Specific Populations Pregnancy: Advise females of the potential risk to a fetus, especially during the second and third trimesters
