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Because of the ambiguity of the ailment, doctors typically cannot identify the exact cause for ones condition but they are associated with increased pressure in the blood vessels in and around the anus

doi:10.1016/S1262-3636(08)73397-4

Foundayo (orforglipron) is the closest thing Eli Lilly has to an oral counterpart, but its a different molecule that only targets GLP-1, not GIP

20 See Table 3: Appendix A: Detailed tables

For example, one patient with POTS (a common autonomic disorder) may have the chief complaint of abdominal pain while the next POTS patient identifies migraine headaches as their primary symptom