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The study shows that in addition to improving glycemic control, GLP-1RAs reduce major adverse renal events in diabetic patients [61]

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GLP-1R is a core member of the G protein-coupled receptor family and is widely distributed on the surface of many human cells (Zheng et al., 2024)

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Gallbladder and gastric emptying: relationship to cholecystokininemia in diabetics

Accordingly, mechanistic interpretations should not be construed as confirmed clinical mechanisms but as explanatory frameworks requiring validation in mechanistic human studies