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Severe abdominal pain, particularly if it is persistent and located in the upper abdomen radiating to the back, requires urgent assessment to exclude pancreatitis, a rare but serious adverse effect of GLP-1 receptor agonists identified in the Wegovy SmPC

Patients should check the specific product information for details about excipients in their medication, as sensitivities to preservatives or other components may contribute to reactions in some individuals

GLP-1 and the Brain: How These Drugs Might Affect Mood and Reward Originally, GLP-1 drugs were valued for their effects on the pancreas and gut, but we now know GLP-1 receptors are also found in the brain

For liraglutide, 21.8% of patients doubled their weight loss, 15.9% lost some additional weight, and 14.2% maintained their loss, with 51.9% in total maintaining or losing more weight

If that sounds familiar, you are not alone

doi: 10.1111/tri.13783