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Most common side effects are GI upset

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Some studies have demonstrated that GLP-1 medication containing tirzepatide may help boost hair regrowth and strengthen hair follicles, while others have established that rapid weight loss associated with semaglutide and tirzepatide can increase hair loss

This anti-autophagic effect of GLP-1 on endothelial cells at an early stage may be crucial for preventing arteriosclerosis which will further lead to serious cardiovascular complications

Similar results were observed for a composite of the kidney-specific components of the primary outcome (HR 0.79, 95% CI 0.660.94) and for death from cardiovascular causes (HR 0.71, 95% CI 0.560.89)

Instead, they offer personalized genetic context that can support more nuanced tolerability discussions