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19 This discrepancy highlights the gap between efficacy observed in controlled trial settings and effectiveness in routine clinical practice
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Within the NHS, Wegovy is offered for weight loss through specialist weight management clinics

Every decision to pause, discontinue, or restart therapy should be based on your current health, treatment goals, laboratory findings, and your providers recommendations

Treatment depends entirely on the underlying diagnosis

Similarly, the association between obesity with cardiovascular disease (CVD), and cognitive decline, in older adults is not definitive

It is not known if intra-islet -cells production of GLP-1 is affected by the surgical procedure or, more importantly, how this axis is impaired in the metabolic syndrome, type 2 diabetes and related pathologies
