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Brain Region Specific Glucagon-like Peptide-1 Receptors Regulate Alcohol-Induced Behaviors in Rodents

Mechanisms involved in this process are both central and peripheral

At the completion of the trial period, body weight loss regardless of dose did not reach a plateau, suggesting more weight loss is possible with longer treatment duration

Rather than stimulating the body to produce more growth hormone, it uses a specific fragment of GH, amino acids 177-191, that retains the fat-metabolizing properties without the growth-promoting effects

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Apovian CM, Aronne L, Rubino D, Still C, Wyatt H, Burns C, Kim D, Dunayevich E