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Clinical research on HFrEF patients shows that GLP-1 agonists enhance left ventricular ejection fraction (LVEF) while reducing fibrosis according to preclinical investigations although clinical trial data for liraglutide remains neutral in FIGHT and LIVE [59,60]

Most plastic surgeons recommend reaching a stable weight before reconstruction surgery and avoiding major weight changes in the months afterwards

[DOI] [PubMed] [Google Scholar] 160.Lyons D, Louly Nathan A, Pender E, Murray G, Smith C, Kirby B, et al

The ongoing Phase 3 ENLIGHTEN-Fibrosis trial in non-cirrhotic (F2F3) MASH and the Phase 3 ENLIGHTEN-Cirrhosis trial in compensated cirrhotic (F4) MASH are actively enrolling patients

For many, the best long-term strategy is combining lifestyle changes with the lowest effective dose of treatment
The behaviour therefore goes beyond just diet
