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OneSource supports this program as the manufacturing partner, enabling end-to-end manufacturing and commercial supply readiness from its US FDA-approved flagship facility in Bengaluru

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The STEP (Semaglutide Treatment Effect in People with Obesity) clinical trial programme demonstrated that adults using semaglutide 2.4 mg weekly alongside lifestyle intervention lost an average of approximately 15% of their body weight over 68 weeks, compared to around 2.4% with placebo. NICE approved Wegovy for use in specialist weight management services in the UK in 2023 (TA875), recognising its clinical effectiveness. Ongoing research continues to explore its cardiovascular benefits, with the SELECT trial showing a significant reduction in major cardiovascular events in people with obesity

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Flexeril (cyclobenzaprine) should be used with caution in patients with reduced kidney function, and dose adjustments should be considered to minimize the ri...
