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However, no significant difference in eGFR was observed between tirzepatide and comparators

GLP-1 drug weight loss, like retatrutide or Ozempic, can lead to loose skin, also known as Ozempic face or Ozempic body. This is a process, not failure

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The adjusted mean change from baseline in body weight was -0.3 kg in patients receiving sitagliptin with metformin immediate-release and insulin and -0.2 kg in patients receiving placebo with metformin immediate-release and insulin

Anyone using oral contraceptives or other hormonal treatments should discuss this with their healthcare professional to ensure their treatment remains suitable