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76 Clinical studies have shown that GLP-1 and its receptor agonist exenatide can improve human bronchial hyperresponsiveness (BHR) by inducing pulmonary vasorelaxation and phosphatidylcholine secretion through activation of the cAMP-PKA-dependent pathway, 77 and by stimulating the secretion of phosphatidylcholine (a major component of surfactant) through cAMP-dependent PKA and cAMP-dependent PKC, thereby improving lung function

She noted that patients with diabetes face a range of oral health complications, including xerostomia, delayed healing, increased infection risk, peri-implantitis and reduced osseointegration of dental implants

Based on current clinical evidence, Mounjaro (tirzepatide) is generally the best tolerated of the available options, with lower rates of nausea compared to semaglutide at equivalent weight loss doses

References: Aroda, V

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