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Some things to know: If you have a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2, semaglutide and tirzepatide may not be right for you

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Timing considerations include avoiding lying down within two to three hours after eating, which can worsen reflux and nausea

Is long-term use expected

doi: 10.1016/j.cmet.2016.06.009

Fatigue sets in
