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Patients with a history of alcohol use disorder should also abstain, as even small amounts may trigger relapse, and the metabolic complications of resumed heavy drinking would be particularly detrimental in the context of diabetes or obesity management

Compounded medications carry additional risks

The Defense Health Agency implemented regulatory controls on weight loss medication coverage effective August 31, 2025

GLP-1, a 36-amino acid peptide, is produced in enteroendocrine L-cells of the distal small bowel and colon (92)

There is no penalty for moving slowly