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Oncogene 36 , 58975909 (2017)

This project will evaluate the safety and efficacy of tezampanel in a rodent model of NOWS with the objective of demonstrating a positive impact on symptomatic relief as well as generating data that can be used to begin discussions with regulatory agencies on clinical development pathways

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Fluid retention may lead to or exacerbate congestive heart failure

This creates a practical constraint: = exceeds 28-day window per reconstitution Solution: Only reconstitute the amount you'll use in 28 days

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