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Cureus 16 , e52670 (2024)

This surprising approach, validated by Amgens human genetics research, may help mitigate the risk of weight rebounda common challenge with current therapiesand could deliver more durable weight loss

95% CI, 1.19-1.47) vs

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While the mechanism underlying the diminished insulin response to GIP in T2D has not yet been fully elucidated, receptor downregulation (55) and desensitization (56) have been suggested as potential causes

In addition, another study found that obese people have higher levels of SCFA (Schwiertz et al., 2010), proving that the level of SCFA is directly proportional to Firmicutes