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This scaffolding allows GPCRs to maintain signaling even when G-protein activity is disabled [61]

[DOI] [PMC free article] [PubMed] 44.Filippatos TD, Panagiotopoulou TV, Elisaf MS

doi: 10.1016/S0140-6736(17)30069-7

This diversity poses a challenge in reaching conclusive findings

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Among several anti-diabetic medications, a systemic review found that GLP-1RAs and Tirzepatide were the most effective in causing weight loss in T2D individuals [92]