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The guidance comes as more than one billion people worldwide currently live with obesity, a number projected to double by 2030 without decisive intervention.

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Plasma concentrations of semaglutide were determined using a validated liquid chromatography-tandem mass spectrometry (LCMS/MS) method

A retrospective disproportionality analysis was conducted using the reporting odds ratio (ROR) on FAERS data (20042024), with Bayesian confidence propagation neural network (BCPNN) employed for sensitivity analysis