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Further research is needed to more clearly elucidate both if GLP-1-mediated glucose uptake in hepatic tissue is exclusively through extrahepatic GLP-1R activation and if GLP-1R is distributed in human hepatic tissue
TNF-alpha mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimers beta-amyloid oligomers in mice and monkeys

Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinsons disease

doi: 10.1016/j.hjc.2018.11.008 43 Rico-FontalvoJReinaMSolerMJUnigarro-PalaciosMCastaeda-GonzlezJPQuinteroJJet al

It mimics glucagon-like peptide-1, a hormone involved in insulin release, glucagon regulation, appetite signaling, and slower stomach emptying
