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Furosemide The estimated ratio for the AUC 0- of furosemide co-administered with oral semaglutide compared with the AUC 0- of furosemide alone was 1.28 and the 90% CI (1.161.42) was not within the pre-specified no effect interval

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It was authorized by EMA in October 2012 and the EU patent is expected to expire in October 2027, whereas crizotinib was authorized by FDA in August 2011 and the US patent is expected to expire in November 2026