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We comprehensively mapped the benefits and risks of GLP-1 receptor agonists (GLP-1) (Ozempic, Wegovy, Mounjaro, Zepbound)

GLP-1 receptor agonists (GLP-1 RAs) with exenatide b.i.d

Berberine is a plant alkaloid affecting glucose metabolism at the cellular level, while GLP-1 agonists regulate appetite and insulin secretion through hormone signaling

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Recent advancementsincluding the approval of oral semaglutide (Rybelsus)have demonstrated the potential for effective oral peptide delivery, though such formulations still face significant pharmacokinetic and formulation-related challenges