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tirzepatide off patent Off-patent semaglutide in 2026: the next revolution in anti-obesity medications F.D.A. Approves New Obesity Drug
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Obesity has a negative effect on reproductive potential primarily due to functional alterations of the hypothalamic-pituitary-ovarian (HPO) axis

Re-evaluating the treatment plan often helps figure out the next steps

At the same time, the incidence of diabetic nephropathy, although reduced compared to 20 years ago, is stabilized in recent years, and the incidence of end-stage renal disease (due to reduced cardiovascular mortality and increased life expectancy) is increasing [64]

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3 Follow-up data from the SURMOUNT-4 trial shows the weight loss is maintained at 88 weeks with continued use
