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Human islet experiments were conducted based on equipment capabilities and experiment design

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doi: 10.1038/nm1196-1254

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infusion of liraglutide inhibits eating in rats by directly activating hypothalamic Pomc/Cart neurons in the ARC, without activating GLP-1-producing neurons in the hindbrain, and independent of GLP-1R signaling in vagal afferents, the area postrema (AP) and the PVN [686]

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