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Session Information Date: Sunday, October 26, 2025 Title: (04300469) Rheumatoid Arthritis Diagnosis, Manifestations, and Outcomes Poster I Session Type: Poster Session A Session Time: 10:30AM-12:30PM Background/Purpose: Obesity significantly increases cardiovascular morbidity and mortality in rheumatoid arthritis (RA), yet effective strategies for managing obesity-related risks in this population remain limited

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Data for HbA 1c and body weight were combined for visits that occurred at different weeks in the two trials, with a variation of up to 6 weeks

Baseline liver function testing before starting semaglutide and periodic monitoring during treatment is standard clinical practice

Other research suggests that tapering off slowly instead of stopping abruptly helps maintain results, and additional data show many people keep at least part of the weight off a year later

If cramping persists beyond 8 weeks or worsens, contact your healthcare provider to discuss potential adjustments