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[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Calkin C., McClelland C., Cairns K., Kamintsky L., Friedman A

Enhanced Exercise Capacity: Studies have indicated that MOTS-c may improve physical performance and endurance, potentially by optimizing mitochondrial function and energy utilization during physical activity

The FDA first authorized Alosetron in 2000 to treat IBS-D in women

Available from: Accessed: 10 Jun 2025 European Medicines Agency (2023) Guideline on clinical investigation of medicinal products in the treatment or prevention of diabetes mellitus

This can be done in conjunction with a consultation for surgical treatments or as a standalone procedure

However, these results were not replicated in a larger multicenter trial conducted over 96 weeks (61)