cramps on semaglutide How to Deal With Nausea and Stomach Issues Semaglutide and Leg Cramps: Causes,
Description
In the STEP 1 trial, adults taking semaglutide lost about 15% of their body weight on average over 68 weeks (Source: NEJM, STEP 1 trial)

Those with pre-existing gastrointestinal conditions, such as irritable bowel syndrome or inflammatory bowel disease, should receive individualised guidance from a registered dietitian, as standard fibre recommendations may require modification (for example, emphasising soluble fibre or considering a dietitian-supervised low FODMAP approach)
If your fatigue is secondary to obesity or metabolic dysfunction, weight loss may help

While this falls within ranges seen with other weight loss interventions, it raises questions about optimizing the quality of weight loss for those particularly concerned about muscle preservation

By mimicking the naturally occurring GLP-1 hormone, semaglutide reduces appetite and aids in sustainable weight loss
If you suspect an adverse reaction to Ozempic, report it to the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)
