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And our current thinking about obesity, and one of the components of the disease of obesity, is that some individuals although they all have GLP-1 and these other gut hormones, amylin, glucagon, GIP, that's what they're called that signal, for some reason, is not getting to the brain in ample amounts to tell the individual to feel full, satiated, and stop eating

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Patients should maintain adequate hydration, especially during the initial weeks when nausea may reduce fluid intake, and continue balanced nutrition despite reduced appetite to ensure adequate protein and micronutrient intake

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