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If that argument implicitly limited the claim to excipients not disclosed in the prior art, a generic manufacturer using a different excipient may be able to design around the patent without triggering literal infringement, and prosecution history estoppel may prevent the infringement claim based on equivalents

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Still, psychiatrists like Georgios Schoretsanitis at the University of Zurich and Chiara Gastaldon at the University of Verona saw a need for additional analyses while the regulatory agencies were reviewing their own datasets

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