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The difference lies in the dose and what each is licensed to treat

doi: 10.1016/j.bbrc.2009.10.054 41 Portela-GomesGMHoogA

So, If you were on lower Mounjaro doses (2.5mg5mg), youll typically start Wegovy at 0.25mg0.5mg If you were on mid-range doses (7.5mg10mg), a starting point of 0.5mg1mg is more common If you were on higher doses (12.5mg15mg), your prescriber may consider starting at 1mg, though this is always an individual clinical decision As we said earlier, this isnt a step backwards

GLP-1 is known for its many metabolic functions, such as helping glucose-dependent insulin secretion [22], reducing hunger [23], slowing down the emptying of the stomach [24], stimulation of -cell proliferation [25], increasing natriuretic and diuretic activities [26], and helping people sleep [27]

This link is essential for understanding why physiological mechanisms alone cannot explain treatment trajectories and why psychological processes must be considered to provide an integrated biopsychosocial model

Of note, while obesity has been a health issue in high-income countries for many years, the greatest rise in its incidence is now seen in low- and middle-income countries