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Description
The tumor uptake values of our PEGylated probe at 60-min post-injection in the resected organs of mice bearing INS-1 xenografts (Right thigh: 37.3 4.5%ID/g, Inside pancreas: 37.7 4.4%ID/g) showed comparable or higher values than those of other 18 F-labeled non-PEGylated modified exendin-4 probes
+ Not necessarily
As we already mentioned, the difference between "twice a day" and "every 12 hours" can be very impactful, even if the patient doesn't know why
Weakly informative priors were used
In the context of DR, this leads to the phosphorylation of ERK1/2, increasing downstream expression of anti-apoptotic genes like BCL2 and reducing the activity of pro-apoptotic markers such as Caspase-3
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