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Surgical Interventions for Severe Cases Orbital decompression: Creating space in the eye socket to reduce protrusion

Cell Metab 13: 320330, 2011

They were assigned 10 or 15 mg of tirzepatide or placebo for 52 weeks

Action of glucagon-like peptide-1 (GLP-1) in humans.

This may further support a more prominent role for GLP1 receptor induced hypophagia via MC 4 receptor+ neurons over oxytocin+ or CRH+ neurons

Consistent with this, following intravenous administration of 11 C-metformin, none of the biguanide can be detected in muscle (64)
