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If you're planning to conceive, discuss discontinuing GLP-1 therapy with your healthcare provider beforehand

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Conclusion GLP-1 receptor agonists represent a paradigm shift in the treatment of metabolic diseases, combining strong clinical outcomes with significant commercial opportunity

doi: 10.1038/s41580-019-0180-9

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If approved, orforglipron would be the first oral GLP-1 therapy with efficacy comparable to injectables , potentially redefining obesity and diabetes treatment worldwide