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Description
2.5.14 MAP3K8/TPL2 inhibition 2.5.14.1 Tilpisertib MAP3K8 (also known as TPL2) is a serine/threonine kinase that regulates inflammatory responses downstream of TLRs and TNF receptors, controlling production of pro-inflammatory mediators including TNF-, IL-1, and COX-2 in UC

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