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Author: Shane Straight, Principal Chemist, OPS Peptide Science Reviewed: May 2026

We elucidated previously unnoted ways in which GLP-1RAs curbed RA pathology via direct suppression of the cGAS-STING signaling pathway to inhibit chondrocyte ferroptosis and concomitantly induced macrophage M2 polarization

With diabetes and CKD projected to be the seventh and fifth leading cause of premature mortality worldwide by 2040, respectively [7], novel and effective treatment options are critical

Glucagon receptor activation increases energy expenditure and promotes hepatic fat oxidation
