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[16] DPP-4 inhibitors (such as sitagliptin), which enhance incretin activity through a different mechanism Insulin therapy, particularly if oral agents and other injectables are unsuitable Traditional agents like metformin, sulphonylureas, or pioglitazone, depending on individual circumstances NICE guideline NG28 recommends individualised treatment approaches based on HbA1c targets, cardiovascular risk, renal function, and patient preferences

Identity Transitions : Mental health professionals are developing specialized approaches for helping patients navigate the psychological aspects of rapid physical transformation, including changes in how others perceive and interact with them

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Furthermore, newer technologies are allowing us to manipulate the activity of cell populations on demand (chemogenetics and optogenetics) that will probably be important in understanding changes in the central nervous system and feeding behavior after surgery

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